Abstract: A low-temperature and oil-resistant nitrile rubber compound and its preparation method, which includes the following components by weight: 100 parts of nitrile rubber, 1-10 parts of active agent, 0.05-5 parts of antioxidant, 30-50 parts of reinforcing agent, 5-20 parts of plasticizer, 1-2 parts of vulcanizing agent, 1-5 parts of accelerator, and 1-10 parts of spherical silica nanopowder, wherein the particle size of silica nanopowder is <80 nm and the surface has a silicon oxide passivation film. -20 parts, 1-2 parts of vulcanizing agent, 1-5 parts of accelerator, and 1-10 parts of spherical silicon nanopowder, wherein the silicon nanopowder has a particle size of <80 nm and a silicon oxide passivation film on the surface. Due to the Si-O bond (0.166 nm) and large Si-O-Si bond angle (135°-144°) in the nano-silica powder, the internal rotation resistance is low and the flexibility is high, and the silicon material is used to modify the nitrile rubber to achieve excellent low-temperature mechanical properties at low temperatures. The product is obtained by mixing each component in order according to the formula through a compactor/kneader and then vulcanizing. The low temperature elasticity of the product of the invention has been effectively improved, low temperature retraction performance has been greatly improved, and the media resistance has been improved, which can improve the low temperature performance of nitrile rubber and media resistance conflict, its preparation process is simple, the conditions can be controlled, and can be prepared in the conventional industrial production line.